![]() ![]() ![]() This preparation has been studied for its ability to transport progesterone into and through human skin. The formulation used is determined by the physician, patient, and pharmacist-the triad relationship. Compounded BHRT preparations include oral, topical/transdermal, parenteral, and nasal administration implants and others. Numerous single-drug formulas, as well as multiple-drug formulas, are prescribed and compounded. In some instances, dehydroepiandrosterone also is used. 2ĭiscussion: Bioidentical hormone replacement therapy (BHRT) generally includes the hormones progesterone, estradiol, estrone, estriol, and testosterone. ![]() Quality Control: Quality-control assessment can include theoretical weight compared with actual weight, apparent pH, specific gravity, active drug assay, color, texture–surface, texture–spatula spread, appearance, feel, rheologic properties, and physical observations. Stability: Check with the manufacturer of the VersaBase Cream for a beyond-use date for this preparation. Use: This preparation has been used in hormone replacement therapy. A dispensing-type container works well for these products after it has been calibrated. Geometrically, incorporate the VersaBase Cream and mix well. Mix the progesterone with the pentylene glycol until the mixture is uniform and smooth. Accurately weigh or measure each ingredient. Method of Preparation: Calculate the quantity of each ingredient for the amount to be prepared. ![]()
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